Technologies

Over the past 13 years, GENOMED has developed a number of significant products to purify DNA from bacteria, blood, tissue, solutions, PCR assays and agarose gels. All GENOMED products generate high quality DNA in a time saving manner. To achieve these goals, we have developed different matrices to bind and purify DNA, and we have optimized various procedures to maximize convenience and reliability.

Anion Exchange Resin (IEX-Resin): The highest purity of DNA (ultrapure DNA) is achieved with an anion exchange resin. One IEX-resin developed by GENOMED (patents US 5,843,312; EP 0744025) is called JETSTAR, which generates ultrapure plasmid and cosmid DNA from all types of bacteria. The JETSTAR purified DNA is ideal to be used for transfection, microinjection and fluorescent sequencing.

Silica Membranes and Silica Resin: Both types of matrices are not anion exchange materials, but generate an excellent DNA quality. They are heavily used in small scale preparations to isolate plasmid DNA from bacteria, genomic DNA from blood and tissue, or DNA from solutions, PCR assays and agarose gels. Fluorescent sequencing, restriction analysis, ligation, screening etc. are the major applications. Because plain silica does not remove all endotoxins, plasmid DNA purified with this technology is not suitable for all types of transfection.